![]() ![]() Due to the differences in toxicokinetics as outlined above, the assessment for mercury exposure from dental amalgams therefore should be based on resulting blood levels of mercury and/or urinary excretion of mercury. Therefore, these limits have only limited use for the assessment of mercury emissions from dental amalgams since the exposure in this case is inhalation or ingestion of elemental mercury. ![]() When using these regulatory limits describing safe intakes of mercury (safe as defined to be without toxic effects after lifetime exposure) it should be recognised that many of the values are recommended for dietary intake of mercury ions and methyl mercury. General conclusions concerning correlation between exposure and toxicology ( risk assessment)Ī number of regulatory limits for mercury exposures have been set by various organisations. There is no scientific evidence that any of those elements currently used in dental amalgam restorations constitute a risk of adverse health effects in individuals apart from allergic reactions to the individual elements.ģ.3.5. The elements other than mercury contained with dental amalgam all have their own, different profiles in terms of essentiality and/or toxicology. Oral ingestion of elemental mercury results only in a very limited absorption, typically 200 mg/kg/day) (Klaasen 2001). Since human exposure to mercury from dental amalgams may occur by inhalation of mercury vapour released from the dental fillings into the oral cavity, by ingestion of the released elemental mercury, or swallowing small pieces of amalgam releasing elemental mercury in the alimentary tract, this discussion focuses on the toxicology of elemental mercury. In general, the toxicology of mercury is highly dependent on the route of administration, the exposure conditions and the speciation of the mercury. ![]()
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